| abstract |
The present invention provides a composition particularly useful for the treatment of hypersensitivity, ie, atopic eczema, asthma and IgE-dependent allergy (type I allergy), particularly pollen allergy and house dust allergy. An immunostimulatory nucleic acid such as an unmethylated CpG (cytosine-guanine dinucleotides) -containing oligonucleotide, which is known to enhance B and T cell responses, is virus-like particles such as nanoparticles, microparticles, and liposomes ( VLP) or a composition packaged by non-covalent bonding or the like. In the treatment of hypersensitivity using this composition, administration of a specific antigen or allergen is not required. [Selection figure] None |