http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014009213-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1d29f7ac2c7f9be9f7dae1a83bbb5c92 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-44 |
| filingDate | 2012-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0be3583ddb53ee2ae3624f7711402aeb |
| publicationDate | 2014-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2014009213-A |
| titleOfInvention | Method for producing mitiglinide calcium hydrate |
| abstract | PROBLEM TO BE SOLVED: To purify hardly soluble impurities in a method of hydrolyzing (S) -2-benzyl-3- (cis-hexahydro-2-isoindolinylcarbonyl) propionic acid ester using an alkali metal hydroxide. Provided is a method for producing highly effective mitiglinide calcium hydrate that is suppressed. SOLUTION: The liquidity of a reaction solution obtained by reacting an alkali metal hydroxide with (S) -2-benzyl-3- (cis-hexahydro-2-isoindolinylcarbonyl) propionic acid ester is weakened. After adjusting to the acidic to weakly alkaline range, a calcium chloride reaction is carried out to produce mitiglinide calcium hydrate. [Selection figure] None |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107963989-A |
| priorityDate | 2012-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.