| abstract |
The present invention provides a pharmaceutical composition for oral administration comprising a therapeutically effective amount of a selective factor Xa inhibitor or a pharmaceutically acceptable salt thereof and an enhancer, wherein the enhancer is a medium chain fatty acid, or a medium Provided is a pharmaceutical composition which is a salt, ester, ether or derivative of a chain fatty acid and has a carbon chain length of 4 to 20 carbon atoms. The present invention also provides a method for obtaining a reproducible bioavailability of a selective factor Xa inhibitor in a subject after oral administration, comprising orally administering the pharmaceutical composition. |