| abstract |
Daily transdermal administration of a composition comprising a bioactive androgen to reduce chronic inflammatory pain, increase endogenous opioid peptide levels, and increase pain threshold in subjects with androgen deficiency symptoms Is provided. Furthermore, the present invention also relates to increasing endogenous opioid peptide levels in a human subject by administering an androgen composition to the subject. The present invention also encompasses administering a composition consisting essentially of androgen to treat chronic inflammatory pain in a subject and to increase the pain threshold. |