| abstract |
The present invention relates to compounds, compositions and methods that respond to modulation of HBV gene expression and / or activity and / or modulate the HBV gene expression pathway, testing, diagnosis of traits, diseases and pathologies And compounds, compositions and methods for treatment. Specifically, the present invention is capable of mediating RNA interference (RNAi) on HBV gene expression, or a double-stranded nucleic acid molecule that mediates the RNA interference, eg, small interfering nucleic acid (siNA), small interfering RNA (siRNA). ), Double-stranded RNA (dsRNA), microRNA (miRNA), and small hairpin RNA (shRNA) molecules. [Selection] Figure 1 |