http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013535694-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-285 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-91215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-56 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2863 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-3955 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 |
| filingDate | 2011-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2013-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2013535694-A |
| titleOfInvention | TAM receptors and TAM receptor ligands in the detection and regulation of neuropathological diseases |
| abstract | Methods, compositions and kits based on TAM receptors, or TAM receptor ligands or agonists are provided for the detection of neuropathological diseases or the determination of their progression. Neurological diseases specifically include multiple sclerosis or other myelopathy characterized by demyelination, oligodendrocyte toxicity and microglial activation. These methods include screening a subject's cells, wherein an increase in TAM receptor expression or a change in TAM receptor ligand expression is diagnostic of the presence or progression of the disease. In addition to treatment of subjects with such neuropathological diseases by administration of TAM receptor ligands (such as GAS6 or protein S) or by administration of agonists such as antibodies specific for TAM receptors Axl, Mer or Tyro3 will be described. |
| priorityDate | 2010-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 108.