| abstract |
An oral controlled-release pharmaceutical composition comprising blonanserin and a controlled-release substance and optionally a pharmaceutically acceptable excipient is provided. Further, the present invention provides blonanserin and release that releases at least about 80% blonanserin within 20 hours when elution is carried out at 50 rpm in 900 ml of 0.1 N HCl, USP type II (paddle) for 20 hours. The present invention relates to a controlled-release pharmaceutical composition containing a controlled substance. The controlled release pharmaceutical composition of the present invention releases 50% blonanserin in about 4-14 hours when elution is performed at 50 rpm in 900 ml of 0.1 N HCl, USP apparatus type II (paddle). |