| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-111
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B5-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
| filingDate |
2011-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2013-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2013532973-A |
| titleOfInvention |
RNA molecules and uses thereof |
| abstract |
The present invention is a method of designing a short RNA molecule to increase the expression of a target gene in a cell by down-regulating a non-coding RNA transcript, comprising a) at least 200 nucleotides upstream of the transcription start site of the target gene. Obtaining a nucleotide sequence of the coding strand of the target gene between 200 nucleotides downstream of the transcription start site of the target gene; b) determining a reverse complementary RNA sequence to the nucleotide sequence determined in step a); c) designing a short RNA molecule that is the reverse complement of a region of the sequence determined in step b) or having at least 80% sequence identity with the reverse complement, said non-coding RNA Methods that do not include a step in which the presence of a transcript is determined, and to such short RNA molecules and uses thereof . [Selection] Figure 1 |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021000119-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021035360-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018512876-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018516545-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10912790-B2 |
| priorityDate |
2010-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |