| abstract |
Provided are newly identified protein fragments of aminoacyl-tRNA synthetases, compositions comprising the polynucleotides encoding them and their complements, related drugs, and their use in diagnostic, drug discovery, research and therapeutic applications. The Embodiments of the present invention generally relate to the discovery of protein fragments of aminoacyl-tRNA synthetase (AARS) that have non-canonical biological activity such as extracellular signaling activity and / or other features related to therapy and diagnosis. . [Selection] Figure 1A |