| abstract |
The present invention relates to sulfonamide derivatives, their use in medicine, compositions containing them, processes for their preparation and intermediates used in such processes. More particularly, the present invention relates to novel sulfonamide Nav1.7 inhibitors of formula 10 (I) :( I) or pharmaceutically acceptable salts thereof, wherein Z, R1, R2, R3, R4 and R5 are As defined in this description. Nav1.7 inhibitors may be useful in the treatment of a wide range of disorders, particularly pain. [Selection figure] None |