| abstract |
The present invention relates to HMG-CoA reductase such as rosuvastatin calcium salt, fluvastatin sodium salt, pitavastatin calcium salt using a novel amide bond-containing compound having the R 2 —N—O—R 1 structure as a core intermediate. Provided is an improved process for producing the inhibitor, wherein the inhibitor is produced under mild conditions. The present invention also provides the novel compound, an intermediate useful for the production thereof, and a production method thereof. |