| abstract |
Formula I below: Wherein ring A, ring B, W, m, D, R 2 , R 2a , R 3 , R 3a and Z are defined as described herein, and pharmaceutically acceptable compounds thereof Salts are inhibitors of Trk kinases and are useful in the treatment of pain, cancer, inflammation, neurodegenerative diseases and certain infectious diseases. Another aspect provides intermediates for preparing compounds of formula I. In one embodiment, a particular compound of formula I may be used as an intermediate for the preparation of another compound of formula I. |