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filingDate 2011-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2013-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2013529199-A
titleOfInvention 2-Aminopyridine derivatives useful as ATR kinase inhibitors
abstract The present invention relates to pyrazine and pyridine compounds useful as inhibitors of ATR protein kinase. The invention also includes pharmaceutically acceptable compositions comprising the compounds of the invention; methods of treating various diseases, disorders, and conditions using the compounds of the invention; for preparing the compounds of the invention Processes; Intermediates for the preparation of compounds of the invention; and studies of kinases in biological and pathological phenomena; studies of intracellular signaling pathways mediated by such kinases; and novel kinase inhibitors Relates to methods of using the compounds in in vitro applications such as comparative evaluation of The compounds of the invention have the formula (III) (wherein the variable groups are as defined herein).
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