abstract |
The present invention relates to an interferon beta sustained-release preparation in which interferon beta, a non-peptide polymer, and an immunoglobulin Fc region are covalently linked to each other and have improved in vivo sustainability and stability, and production thereof Regarding the method. The interferon beta sustained-release preparation of the present invention is useful for various interferon indications since its in vivo activity is maintained at a relatively high level and the blood half-life is greatly increased. [Selection] Figure 1 |