http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013522603-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-775 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-78 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-689 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
filingDate | 2011-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2013-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2013522603-A |
titleOfInvention | Methods for predicting pregnancy loss risk and methods for reducing pregnancy loss risk |
abstract | A method for diagnosing and predicting a subject's risk of pregnancy loss based on the presence of unusual humoral responses to three proteins: apolipoprotein B-100, alpha 2 macroglobulin (alpha 2M), and fibronectin. Disclose. (I) if trophoblast-derived fibronectin and / or maternal IgG antibody against ApoB-100 is present, or if the antibody is at a detectable level, and / or (ii) specific for alpha 2M Absence of bound antibody or undetectable level of antibody is associated with an increased history of RPL and increased risk of pregnancy loss. In addition, a method for identifying a subject at risk of pregnancy loss, each comprising detecting the presence or absence of an antibody against one or more of trophoblast-derived ApoB-100, alpha 2M, and fibronectin; Also disclosed are methods for selecting subjects for study and methods for reducing the risk of pregnancy loss in subjects. Further provided is a kit comprising ApoB-100, alpha 2M, and fibronectin. |
priorityDate | 2010-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 339.