http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013521797-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-28 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0676 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0677 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-00 |
filingDate | 2011-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2013-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2013521797-A |
titleOfInvention | Islet-like tissue culture method using tissue complex of pancreatic non-endocrine epithelial cells and vascular endothelial cells |
abstract | According to embodiments, a method of making insulin producing cells (IPTs) comprises preparing non-endocrine epithelial cells (NEECs) and vascular endothelial cells (VECs) derived from postnatal pancreas, culturing NEECs Culturing VECs in vitro, and generating a tissue complex consisting of NEECs and VECs in vitro, wherein the culturing of VECs is at least partially performed separately from the culture of NEECs. . According to another embodiment, native islets are seeded on a cell monolayer of separately cultured vascular endothelial cells (VECs). According to yet another embodiment, the method of enriching NEECs comprises culturing NEECs adhered to a container or substrate, residual cells that have been detached with tissue dissociating enzymes and still adhered to the container or substrate (LOCs ) And culturing the NEECs in the presence of the LOCs or in a medium conditioned by the LOCs. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020179380-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016093362-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10799615-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2016093362-A1 |
priorityDate | 2010-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 815.