http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013521087-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-06 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09D129-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F8-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0442 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F116-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F16-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B17-12 |
| filingDate | 2011-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2013-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2013521087-A |
| titleOfInvention | Radiopaque, non-biodegradable, water-insoluble, poly (vinyl alcohol) iodinated benzyl ether, process for its preparation, injectable embolic composition containing it, and process for its use |
| abstract | The present invention comprises a radiopaque, non-biodegradable, characterized in that it comprises a poly (vinyl alcohol) having covalently grafted iodinated benzyl groups containing 1 to 4 iodine atoms per benzyl group Water-insoluble, poly (vinyl alcohol) iodinated benzyl ether (iodo-benzyl ether-PVA), 0-100% hydrolyzed poly (vinyl alcohol) with 1 to 4 iodine atoms per benzyl group The method for producing iodo-benzyl ether-PVA according to any one of claims 1 to 7, which comprises a step of reacting with an iodinated benzyl derivative containing benzene in a polar aprotic solvent in the presence of a base under anhydrous conditions. . The iodo-benzyl ether-PVA is particularly useful as an embolic agent in an injectable embolic composition. The invention also relates to an injectable embolic composition comprising the iodo-benzyl ether-PVA and capable of forming aggregates by contact with body fluids by precipitation of the iodo-benzyl ether-PVA. The present invention is particularly useful for forming aggregates in blood vessels in vivo or in tumors. The present invention further relates to a coating composition comprising the above iodo-benzyl ether-PVA and capable of forming a radiopaque coating on a medical device. The invention further relates to particles formed from the above iodo-benzyl ether-PVA. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020073636-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2022023869-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11744916-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021520440-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7095112-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7163471-B2 |
| priorityDate | 2010-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 93.