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filingDate 2011-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2013-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2013516443-A
titleOfInvention Fibrinogen preparation enriched for fibrinogen with extended alpha chain
abstract The present invention relates to a fibrinogen preparation enriched for alpha-extended fibrinogen. Compositions containing such preparations typically show improved coagulation properties compared to preparations based on HMW Fi containing no or very little α-extended fibrinogen. Specifically, the clot formation time and clot strength of clots made with α-extended fibrinogen are improved. Furthermore, plasmin-mediated degeneration of alpha-extended fibrinogen is reduced compared to plasma derived fibrinogen. [Selection figure] None
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