| abstract |
Synthetic methods for preparing deoxycholic acid and its intermediates, high purity synthetic deoxycholic acid, compositions, and methods of use are provided. Further provided is a process for the synthesis of 12-keto or 12-α-hydroxy steroids from Δ-9,11-ene, 11-keto or 11-hydroxy-β-steroids. The invention further relates to novel compounds prepared during the synthesis. The invention also relates to the synthesis of deoxycholic acid starting from hydrocortisone. |