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filingDate 2009-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2013-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2013513603-A
titleOfInvention Immunogens, their preparation and use in polyclonal antibody production systems
abstract The present invention relates to a fusion protein comprising the amino acid sequence of fragment H corresponding to a fragment of a calcium binding protein excreted or secreted by an adult fluke, followed by an amino acid sequence corresponding to an unrelated protein or protein fragment, pharmaceutical composition , Vaccines and adjuvants including immunogens, preparation methods, other methods and uses of antibody production. The present invention relates to the preparation of immunogens by the addition of peptide sequences. The present invention is useful for producing an immune response by increasing the specific antibody titer in serum against a protein or other antigen, and is particularly applicable to the production of specific polyclonal antibodies, immunotherapy, and immune defense. The production of a recombinant protein containing the polypeptide or the addition of the polypeptide to the target antigen by fusion of the polypeptide with the target antigen is immunity induced by introduction of the molecule into a subject susceptible to infection due to antibody production. Induces a significant increase in the immunogenicity of molecules that amplify the response.
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