http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013513552-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65616 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-675 |
| filingDate | 2010-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2013-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2013513552-A |
| titleOfInvention | Acyclic nucleoside phosphonate derivatives and their medical applications |
| abstract | The present invention relates to an acyclic nucleoside phosphonate derivative and its medical use. Specifically, the present invention provides a compound of formula I (wherein having potent activity and low cytotoxicity against viruses such as hepatitis B virus, R 1 is H or methyl; each R 2 is, Independently a —R 3 or —OR 3 ; each R 3 is independently a C 1 -C 8 alkyl, C 3 -C 8 cycloalkyl), or acyclic nucleoside phosphonate derivative, or It relates to a pharmaceutically acceptable salt, isomer, hydrate or solvate thereof. The invention further relates to a process for preparing the compounds of formula I, pharmaceutical compositions comprising said compounds and medical uses of said compounds. The acyclic nucleoside phosphonate derivatives of the present invention have activity against viruses such as hepatitis B virus and good in vivo behavioral properties. |
| priorityDate | 2009-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 222.