abstract |
Structure (I): (I) Wherein X, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 and R 7 are as defined herein. ], Its stereoisomers, and pharmaceutically acceptable salts. Such compounds have activity as SHIP1 modulators and can therefore be used to treat any of a variety of diseases, disorders or conditions that would benefit from SHIP1 modulation. A composition comprising a compound of structure (I) in combination with a pharmaceutically acceptable carrier or diluent also modulates SHIP1 by administering such a compound to an animal in need thereof Is disclosed as a method. |