abstract |
The present invention provides novel compounds characterized as Rho kinase (ROCK) inhibitors, methods for discovering such compounds, and their therapeutic, research and diagnostic uses. In particular, the present invention relates to 1,4-benzodiazepine-2,5-dione and related compounds having ROCK inhibitory activity, and methods of using such compounds as therapeutic agents to treat many conditions associated with ROCK activity. I will provide a. |