abstract |
Compounds are provided that selectively modulate the sphingosine-1-phosphate receptor, comprising a compound that modulates subtype 1 of the S1P receptor. Methods for the asymmetric synthesis of such compounds are provided. Use, treatment or treatment of a composition of the present invention comprising a compound of the present invention for the treatment or prevention of disease, illness, and disease where modulation of sphingosine-1-phosphate receptor is medically required Prophylactic and preparation methods are provided. |