abstract |
The present invention provides a pharmaceutical formulation useful for oral administration of a compound of formula (I) or a pharmaceutically acceptable salt thereof (eg, IPI-926) to a human or animal subject. Increasing the particle size of IPI-926 increases both the degree of dissolution and the dissolution rate of IPI-926. A pharmaceutical formulation can also include one or more other pharmaceutically acceptable fillers, binders, surfactants, disintegrants and one or more other therapeutic agents, and the like. The present invention also provides methods for preparing and using the pharmaceutical formulations. [Selection figure] None |