http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013509878-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B50-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-102 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1034 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-531 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B30-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate | 2010-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2013-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2013509878-A |
| titleOfInvention | Method for producing improved antigen-binding agent using chain shuffling and optionally somatic hypermutation |
| abstract | The present invention relates to a method for identifying a desired antigen-binding substance that binds to a target antigen. The method utilizes a combinatorial approach, wherein a nucleic acid sequence encoding a polypeptide comprising a first component of an antigen-binding agent comprises a nucleic acid encoding a polypeptide each comprising a second component of the antigen-binding agent. Provided to the cell population along with a library of sequences. The method further includes subjecting the one or more nucleic acid sequences encoding the first component, the second component, and / or the identified antigen binding agent to somatic hypermutation. [Selection figure] None |
| priorityDate | 2009-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 344.