abstract |
Formula (I) (I) Disclosed is a compound of the formula wherein X 1 , X 2 , X 3 , W, Q 1 , Q 2 and G 2 are as defined herein, or a stereoisomer or salt thereof. Also disclosed are methods of using such compounds as selective agonists for the G protein coupled receptor S1P 1 as well as pharmaceutical compositions comprising such compounds. These compounds are effective in treating and preventing a disease or disorder at various treatment sites, such as autoimmune diseases and vascular diseases, and delaying its progression. |