| abstract |
[Chemical 1] The present invention relates to novel imidazo [1,2-b] pyridazine derivatives that are inhibitors of phosphodiesterase 10 enzyme (PDE) and are useful in the treatment or prevention of neurological, mental and metabolic disorders involving the PDE10 enzyme. The present invention also relates to pharmaceutical compositions comprising such compounds, methods of making such compounds and compositions, and to the prevention or treatment of such compounds or pharmaceutical compositions for neurological, mental and metabolic disorders and diseases. Also directed to use. |