Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70596 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57492 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57407 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-04 |
filingDate |
2010-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2013-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2013508679-A |
titleOfInvention |
Predicting tivozanib response |
abstract |
A diagnostic method for predicting whether a human tumor is sensitive or resistant to treatment with tivozanib (AV-951) is disclosed. The method is based on the measurement of macrophage content in tissue samples from tumors. Measurement of macrophage content can be based on analysis of macrophage marker gene expression, for example, by RNA analysis or immunohistochemistry. The present invention provides, for example, a method for identifying tumors that are resistant to treatment with tivozanib. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015210268-A |
priorityDate |
2009-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |