http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013505227-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 |
| filingDate | 2010-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2013-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2013505227-A |
| titleOfInvention | 5-Phenylpyrazolopyridine derivatives, their preparation and therapeutic use |
| abstract | Formula (I) Wherein R 1 is halogen, (C 1 -C 6 ) alkyl, halo (C 1 -C 6 ) alkyl, (C 1 -C 6 ) alkoxy, halo (C 1 -C 6 ) alkoxy, (C 1 -C 6) thioalkyl, -S (O) (C 1 -C 6) alkyl, -S (O) 2 (C 1 -C 6) alkyl, hydroxyl, hydroxy (C 1 -C 6) alkylene, CHO, COOH , (C 1 -C 6 ) alkoxy (C 1 -C 6 ) alkyleneoxy, NRaRb, CONRaRb, SO 2 NRaRb, NRcCORd, OC (O) NRaRb, OCO (C 1 -C 6 ) alkyl, NRcC (O) ORe or optionally substituted from NRcSO 2 Re by one or more atoms or groups selected independently of one another represent a phenyl group or a naphthyl group, X is, Unlike also the same in the stomach, represent hydrogen, halogen, (C 1 -C 6) alkyl or (C 1 -C 6) 1 to 4 substituents selected from alkoxy, (C 1 -C 6) Alkyl can be optionally substituted by one or more groups selected from halogen, (C 1 -C 6 ) alkoxy or hydroxyl, and R 2 and R 3 independently of one another are a hydrogen atom, Rf group Represents a (C 1 -C 6 ) alkyl group or a CHO or COOH group optionally substituted by X and R 3 together with the carbon atom carrying them form a carbocycle of 5 to 7 carbon atoms it can be, R4 represents a hydrogen atom or a (C 1 -C 6) alkyl groups, independently Ra and Rb are each a hydrogen atom or a (C 1 -C 6) alkyl , Aryl (C 1 -C 6) alkylene or aryl group, or Ra and Rb together with the nitrogen atom carrying them, (C 1 -C 6) alkyl, aryl or aryl (C 1 -C 6 ) Form an azetidine, pyrrolidine, piperazine, azepine, morpholine, thiomorpholine, piperazine or homopiperazine group, optionally substituted by an alkylene group, and Rc and Rd are independently of each other a hydrogen atom or (C 1 -C 6 ) Represents an alkyl, aryl (C 1 -C 6 ) alkylene or aryl group, or Rc and Rd together form a (C 2 -C 5 ) alkylene group, and Re represents (C 1 -C 6 ) alkyl aryl (C 1 -C 6) alkylene or aryl group, or Rc and Re, one To form a (C 2 -C 5) alkylene group, Rf is selected from the group consisting represents hydroxyl, oxo, a CHO or COOH group. ), In the form of addition salts with bases or acids. Therapeutic uses and synthetic methods. |
| priorityDate | 2009-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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