| abstract |
Disclosed herein are compositions and methods for tissue-specific targeted delivery of therapeutic agents through the use of tissue-specific peptidomimetic ligands. The ligand comprises a composition of formula A-scaffold-A 'and one or more hydrophobic anchors covalently bound to the scaffold. The compounds according to A and A ′ linked to the scaffold are each monovalent peptidomimetic compound is fragment IK, GK, ID, GS, GT, VS, TK, KT, AR, KI, KE, AE, GR, YS, IR and monovalent peptidomimetic compounds selected from the group consisting of morpholinos. |