abstract |
The present invention relates to a compound of formula (I), or a pharmaceutically acceptable salt thereof, wherein R 1A , R 1B , R 1C , R 2 , R 3 , R 4 , R 5 , R A , R B , R C and X are as described herein. These novel benzimidazole derivatives are useful in therapy, particularly for treating diseases or conditions mediated by SMO, including the treatment of abnormal cell proliferation such as cancer in mammals. The invention also relates to methods of using such compounds for the treatment of abnormal cell growth in mammals, particularly humans, and pharmaceutical compositions containing such compounds. [Chemical 1] |