| abstract |
The present invention relates to a method for determining the state of epithelial differentiation of human keratinocytes in a sample of human epithelium, comprising hsa-miR-455-3p, hsa-miR-141, hsa in said keratinocytes. -MiR-148a, hsa-miR-182, hsa-miR-224, hsa-miR-26a, hsa-miR-26b, hsa-miR-361-5p, hsa-miR-425, hsa-miR-92b, hsa -Let-7i, hsa-miR-22, hsa-miR-221, hsa-miR-222, hsa-miR-29a, hsa-miR-29b, hsa-miR-663, hsa-miR-30a and hsa-miR Determining the expression level of at least one miRNA selected from -30c, and determining the expression level of the selected miRNA Preferably said method comprising comparing the same strain or obtained from the same population, undifferentiated keratinocytes, or average level of expression of a miRNA selected in differentiated epithelial keratinocytes cells. The invention also relates to a method for determining the state of epithelial differentiation and the use of a pharmaceutical or cosmetic composition. |