http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013502401-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-454 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C303-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-08 |
| filingDate | 2010-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2013-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2013502401-A |
| titleOfInvention | Method for synthesizing naratriptan |
| abstract | The present invention relates to a process for producing naratriptan or a salt thereof, which comprises: (a) reacting a compound of formula (3) with a compound of formula HCCR (wherein Z is a protecting group and Y is a deprotection group). And R is a trialkylsilyl group, a trialkylstannyl group or a zinc (II) halide), a step of obtaining a compound of formula (4); (b) a compound of formula (4) A compound of formula (5) wherein Z ′ is hydrogen or a benzyl group; (c) a compound of formula (5) is converted to naratriptan; and (d) Optionally converting naratriptan to its salt. The present invention also provides novel compounds (3) and (4) and methods for producing them. [Chemical 1] [Selection figure] None |
| priorityDate | 2009-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 201.