abstract |
The present invention provides methods for the synthesis and / or purification of certain 3,7-diaminophenothiazine-5-ium compounds, including methylthioninium chloride (MTC), and their use in methods of inactivating pathogens. A step of producing a corresponding acyl compound. Then deacylating and optionally purifying. A process comprising: sequentially oxidizing a deacylated compound to obtain the diaminophenothiazinium compound; and optionally purifying the diaminophenothiazinium compound. [Selection figure] None |