abstract |
Disclosed is a formulation comprising a dipeptidyl peptidase (DPP) -IV inhibitor and metformin in the form of a free-flowing, agglomerated tablet powder that can be easily granulated or compressed into tablets. A tablet comprising preferably vildagliptin and metformin or a pharmaceutically acceptable salt thereof in each case as a DPP-IV inhibitor and containing between 50 and 96% by weight of active ingredient based on dry weight . Metformin is preferably in the form of granules containing a binder. As the binder, starch is used as the binder; cellulose and its derivatives; sucrose and the like. The form of metformin is a granule. The form of vildagliptin is a particle. [Selection figure] None |