| abstract |
Compositions and methods are provided for promoting bone growth and increasing bone density, and for treating multiple myeloma. An activin receptor type IIa (ActRIIa) protein and an immunoglobulin that binds to an activin receptor type IIa (ActRIIa) ligand with a KD of at least 10-7 M and has the effect of inhibiting ActRIIa signaling in cells A pharmaceutical composition comprising a fusion protein with an Fc moiety. [Selection figure] None |