| abstract |
[PROBLEMS] To reliably form a minute flow path through which a valuable biological sample or a dilute and minute amount of a reagent flows, so that the flowed sample does not break even when pressurized and flowed, and accurately and reliably flows as desired. Providing simple and small microchemical chips that can be sent to the road, and can accurately and easily analyze and react to useful substances such as biocomponents in the specimen in a short period of time, and can be manufactured in large quantities and homogeneously with high yield. To do. A microchemical chip 1 includes a base material made of metal, ceramics, glass, or resin, in which a flow path 26 that pressurizes and flows a fluid sample selected from a specimen and a reagent to cause a chemical reaction penetrates the rubber sheet 20. The rubber sheet 20 is sandwiched between the sheets 10 and 30 and joined to the base sheets 10 and 30 directly on the front and back surfaces or by chemical bonding via a silane coupling agent, and a fluid sample is injected into the flow path 26. Holes 11 a, 11 b and holes 12 a, 12 b, 12 c for discharging the flowed sample are opened in the substrate sheet 10. [Selection] Figure 1 |