| abstract |
[PROBLEMS] To find a fusion protein (or a protein interaction specifically seen in cancer cells) that is specifically expressed in more cancers, and to prevent or treat cancer that can exert a therapeutic effect specifically in cancer cells. Provide a means. According to one aspect of the present invention, cancer containing one or more selected from the group consisting of SAP155 inhibitors, FIR-SAP155 inhibitors, and FIRΔexon2-SAP155 inhibitors as an active ingredient. Prophylactic and / or therapeutic agents are provided. According to another aspect of the present invention, the step of bringing a test substance into contact with at least one of SAP155, FIR, and FIRΔexon2, and the function of the test substance at least one of SAP155, FIR, and FIRΔexon2, or A method for identifying a candidate substance for a prophylactic and / or therapeutic agent for cancer, comprising the step of determining whether to inhibit at least one of the binding between SAP155 and FIR, or the binding between SAP155 and FIRΔexon2. The [Selection] Figure 7 |