http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013176397-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_031b407a6c144a91e91831eeb958d415
classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16
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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
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filingDate 2013-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fdac8feb51bffebef4fc368f96b35bc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbf5929793bbd73585a1cb1cc48fbbce
publicationDate 2013-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2013176397-A
titleOfInvention Molecular prognostic signature and its use to predict distant metastasis of breast cancer
abstract The present invention provides a molecular prognostic signature and its use for predicting distant metastasis of breast cancer. The present invention is based on a unique 14 gene molecular prognostic signature that is useful for predicting breast cancer metastasis. In particular, the present invention relates to methods and reagents for detecting and analyzing the expression levels of these genes, and methods of using expression level information to predict the risk of breast cancer metastasis. In one aspect of the invention, the genes known as CENPA, PKMYT1, MELK, MYBL2, BUB1, RACGAP1, TK1, UBE2S, DC13, RFC4, PRR11, DIAPH3, ORC6L and CCNB1 in estrogen receptor positive tumor cells of breast cancer patients It relates to a method for measuring the risk associated with tumor metastasis in breast cancer patients, comprising measuring mRNA expression and predicting the risk of tumor metastasis based on the mRNA expression level of these genes. [Selection figure] None
priorityDate 2007-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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