| abstract |
Biodegradable compositions for delivering bioactive substances are provided. The biodegradable composition of the present invention comprises a reaction product of a reaction mixture comprising an aldehyde polymer solution, a crosslinked hydrazide, and a biologically active substance, and the biological product containing the reaction product contained therein. A composition is a hydrazide crosslinked aldehyde polymer matrix with an active substance, and the polymer matrix solidifies in about 1 to 10 minutes. Furthermore, the present invention can be provided in the form of a kit consisting of a double syringe each containing the first and second aliquots of the reaction mixture so that they can be mixed immediately before use. [Selection figure] None |