abstract |
PROBLEM TO BE SOLVED: To prevent this disease by inhibiting the loss of cardiac function, and ideally by improving the cardiac function of a person with congestive heart failure or at risk. The invention features a method of treating or preventing congestive heart failure by administering a polypeptide comprising an epidermal growth factor encoded by a neuregulin gene. The method comprises a method for treating or preventing congestive heart failure in a mammal, comprising administering to the mammal a polypeptoid comprising an epidermal growth factor-like (EGF-like) domain, Wherein the EGF-like domain is encoded by a neuregulin gene, wherein the step of administering is an effective amount to treat or prevent heart failure in the mammal. [Selection figure] None |