abstract |
Provided is the synthesis of sialic acid in a plant. A method for synthesizing sialic acid in a plant and a plant capable of synthesizing sialic acid are provided. Further provided is a method for producing a sialylated protein in a plant. A method of synthesizing sialic acid includes providing a plant comprising a nucleotide sequence encoding N-acetylneuraminic acid (Neu5Ac) synthase or Neu5Ac lyase and expressing the nucleotide sequence thereby synthesizing sialic acid. Including that. The plant may co-express a nucleotide sequence encoding one or more of epimerase, CMP-Neu5Ac synthase, CMP-Neu5Ac transporter and sialyltransferase. [Selection] Figure 1 |