http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013112675-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8672dbc019ff192d2e20697055921d28 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 |
filingDate | 2011-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dda68edac39fde0d26dc783ee452f5c5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9101e83fbe69bdad289ae589355500c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc654b6bd9e9fc94953cc371c292a51a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b328bc08e7bd5b5c9b1761ae2771696d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8de9076006fd1ae2520751ccfc0f92eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_108c21d8e0d5993c0e913b320dbbff8b |
publicationDate | 2013-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2013112675-A |
titleOfInvention | Stabilized candesartan-containing drug composition |
abstract | It has been known that candesartan cilexetil preparations lose the stability of active ingredients due to the collapse of the three-dimensional structure of crystals during the manufacturing process such as tableting. A decrease in the stability of the active ingredient causes generation of related substances, leading to a decrease in the content of the active ingredient. For this reason, there is a concern that a stable therapeutic effect cannot be obtained after long-term storage. Therefore, stabilization of the active ingredient in the candesartan cilexetil formulation has been demanded. [Solution] By containing a lower alcohol in the candesartan cilexetil preparation, a drug composition having excellent storage stability and stable active ingredient content over a long period of time can be provided. Thereby, the above-mentioned problem is solved. [Selection figure] None |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-5844929-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112957336-A |
priorityDate | 2011-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.