abstract |
A transdermal delivery system for administering sufentanil through the skin. The system contains a sufficient amount of sufentanil to induce and maintain a state of analgesia when applied to a subject, and the dosage form rate control over the sufentanil flux from the system Is high, the net flux of sufentanil through the skin from the system is high, the penetration enhancer that is an adhesive member with excellent shear time is unnecessary, and the coefficient of variation of the net flux of sufentanil from the system is Has one or more characteristics, including smallness, high delivery efficiency, and substantially constant steady state net flux of sufentanil from the system, and painlessness when applied to a subject Of a transdermal delivery system for administering sufentanil in an amount sufficient to induce and maintain a long term. [Selection figure] None |