| abstract |
The present invention provides a trifunctional bispecific antibody for producing a pharmaceutical composition for prevention and treatment of neoplastic diseases. (A) a property of binding to T cells; (b) binding to at least one tumor-associated antigen on a tumor cell, said antigen being Her2 / neu, CD20, EpCAM, G250, GD2, GD3, proteoglycan A function selected from the group consisting of MHC II, EGF-R and CEA; (c) a property of binding to Fcγ receptor type I and / or type III positive cells through the Fc region; Sex antibody. [Selection figure] None |