| abstract |
The present invention relates to a reversible and selective inhibitor of type 2 methionine aminopeptidase, which is a pathological condition involving reactivation of lung and liver fibrosis, angiogenesis, such as diabetic retinopathy, age-related macular degeneration, A novel compound effective for psoriasis, cancer and the like, and a pharmaceutical composition containing the compound. A compound represented by formula (I) and a pharmaceutical composition containing the compound. (Wherein R1 represents an alkyl group having 1 to 4 carbon atoms, R2 represents a pyridyloxy group, pyridylamino group, etc., and R3 represents hydrogen, halogen, an alkyl group having 1 to 6 carbon atoms, a carboxyl group, or the like. ) [Selection figure] None |