| abstract |
The present invention relates to a disorder in which intracellular calcium homeostasis such as arrhythmia, heart failure and stroke is prevented by inhibiting sodium / calcium exchanger (NCX), particularly sodium / calcium exchanger subtype 1 (NCX1). Providing a compound, as well as a method for producing the compound, its use as a medicament, and a pharmaceutical composition comprising it. A substituted 2- (chroman-6-yloxy) -thiazole compound represented by the following general formula I: [Selection figure] None |