Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e0d0ee35d4a877b3c8fffe658303ee3 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08H1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K17-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-26 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-00 |
filingDate |
2012-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f814684ff7f9b286fd583af9b9f3a1ac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c51b4d27a479af65ae01831b58695ee8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ef4426e6cbd83fbaefa6d7dfaa4c0df |
publicationDate |
2013-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2013049860-A |
titleOfInvention |
Activated sialic acid derivatives for derivatization and binding of proteins |
abstract |
PROBLEM TO BE SOLVED: To provide a protein therapeutic agent having improved pharmacokinetic properties using natural PSA. A PSA derivative is synthesized by converting a reducing terminal and / or a non-reducing terminal sialic acid unit into an N-hydroxysuccinimide (NHS) group. Non-crosslinked / crosslinked polysialylated compounds formed by reacting this derivative with a therapeutic drug, peptide or protein, or substrate containing a drug delivery system amine group or hydrazine group. [Selection figure] None |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014040601-A |
priorityDate |
2005-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |