| abstract |
Provided is a cancer treatment using viruses and camptothecins. A mammalian subject having a neoplasm is treated with a virus and a camptothecin compound (eg, irinotecan or topotecan). The virus is selected from the group consisting of Newcastle disease virus, measles virus, vesicular stomatitis virus, influenza virus, Sindbis virus, picornavirus, and myxoma virus. This treatment can also include the step of administering a monoclonal antibody (eg, cetuximab) to the epidermal growth factor receptor. [Selection figure] None |